Fmoc-R-3-Amino-3-(3-bromo-phenyl)-propionic acid is an organic compound that can be used to synthesize polypeptides and proteins. Its molecular formula is C20H16BrNO4 and its molecular weight is 411.25g/mol. The compound has the form of a white to pale yellow solid.
Fmoc-R-3-Amino-3-(3-bromo-phenyl)-propionic acid is commonly used in protecting group and coupling reaction in solid phase synthesis. It can be used as an introducer of amino acid residues for the construction of peptide chains. It can be combined with other amino acids or peptide segments to form polypeptides with specific functions.
The preparation of the compound is usually achieved by organic synthesis methods. First, the desired amino acid is taken and then esterified with 3-bromobenzeneacetic acid to give 3-(3-bromophenyl) propionic acid. Next, the amino group is protected and reacted with Fmoc-OSu to give the desired Fmoc-R-3-amino -3-(3-bromophenyl) propionic acid.
In the use of Fmoc-R-3-amino -3-(3-bromophenyl) propionic acid need to pay attention to some safety matters. The compound may cause irritation to the eyes, skin and respiratory tract. Use chemical protective gloves, goggles and protective masks when handling.
To summarize, Fmoc-R-3-amino -3-(3-bromophenyl) propionic acid is a compound used in the synthesis of polypeptides and proteins. It has a specific structure and properties, which can play an important role in solid phase synthesis. However, it is necessary to pay attention to safe operation and protective measures during use.